Refinex in cosmetology. Efficiency, side effects of use, reviews of cosmetologists

Over time, the skin begins to show signs of aging and expression lines. Withering becomes noticeable to everyone around. This fact is very frustrating for women. To correct the situation, Refinex injections are used. According to the reviews of cosmetologists, they give a good anti-aging effect.

Before use, it is recommended that you familiarize yourself with the action of the product, contraindications and side effects of the procedure.

Chemical composition

The active ingredient of Refinex is botulinum neurotoxin. Thanks to him, the drug has a pronounced muscle relaxant effect. Penetrating into the deep layers of the skin, the substance affects the receptors that are located on the surface membrane of neurons. As a result, the release of the mediator stops entering the synaptic cleft.

1 bottle of the product can contain 50 or 100 units of the active substance. Before use, it goes through step-by-step cleansing procedures. As a result, botulinum toxin crystallizes, dissolves and is filtered again.

After processing, the component is mixed with:

• sucrose;
• dextran;
• gelatin.

The resulting composition is dried, frozen and sublimated. The result is a powder called lyophilisate. It is designed to dissolve. The drug is hypoallergenic.

Act

Refinex has an action that determines the active ingredient. Botulinum toxin is a strong muscle relaxant. It reduces facial muscle tone. Blocking the activity of mimic muscles prevents the appearance of creases and folds in the skin. The effect occurs immediately after the drug enters the layers of the epidermis.

Stages of inhibition of a neuromuscular impulse:

1. Communication with receptors. Lasts for 30 minutes. Molecules of the active substance bind with receptors of glia and neurons, as well as terminals.
2. Endocytosis... Membrane vesicles are formed. They are needed for external capture by cells of the epidermis. The bound butolotoxin penetrates into the fluid inside the cell.
3. Release of acetylcholine... Having reached the space inside the cell, the substance inhibits the synthesis of acetylcholine. It provides the transmission of nerve impulses at the level of the neuromuscular synapse.

Refinex, reviews of cosmetologists about which help to evaluate the effect of the procedure, completely fixes the facial muscles. At the same time, human facial expressions remain natural. The people around do not notice the changes in her.

The drug fills in folds and cracks. It stays under the skin for 2-3 weeks. This time is enough for it to be completely absorbed into the layers of the epidermis. Sucrose and proteins are absorbed into soft tissues. These components bring skin metabolic processes back to normal, activating the natural regeneration of cells.

The musculature stops contracting and relaxes completely. Thanks to this, wrinkles are smoothed out at the injection site, skin tension passes. Deep folds become less noticeable, turgor increases.

People with increased activity of facial muscles experience discomfort and spasms. The effect is aimed at eliminating visual imperfections of the skin, creases and folds. The procedure fights well against wrinkles around the lips, eyes and forehead.

The purpose of the introduction of the substance is:

• strabismus in a paralytic form;
• pathology of the cervical muscles and its constant tension;
• regular closure of the eyelids, which occurs due to the contraction of the circular eye muscles;
• nervous tic.

You should not expect a pronounced anti-aging effect with strong signs of aging. Botulinum toxin for this skin condition has a weak effect.

Serious age-related changes require complex therapy. The active substance is also ineffective in loosening the collagen layer and dehydrating soft tissues.

The result after applying Refinex, depending on the area of ​​administration:

1. Eyelids. Injections make the look more expressive and raise the eyebrows. Helps smooth out wrinkles around the eyes and crow's feet.
2. Forehead... Horizontal folds disappear and the brow line is restored. After the procedure, a lifting of the upper part of the face is observed.
3. The area between the eyebrows... The look ceases to be gloomy and tired due to the smoothing of the vertical fold.
4. Mouth... Small wrinkles are removed, lips acquire a beautiful curve. The drug is rarely injected into this area due to the high likelihood of complications.

A distinctive feature of Refinex from other drugs of a similar action is the infusion of a minimum dose of the finished solution. This feature has a positive effect on the patient's well-being during the session and on the effect itself.

For comparison, facial expressions come to their natural state after 2-4 hours, when Botox injections can disrupt its mobility for 5-7 days after getting under the skin.

Application

The procedure for the introduction of Refinex does not imply serious preparatory measures.

There are some rules to follow before using:

1. 2-3 days before it is recommended to stop taking medications that affect the ability of blood to clot. It is important to abandon aminoglycoside, erythromycin and tetracycline antibiotics in order not to get an enhanced effect of the injection.
2. 7 days before the session, it is necessary to exclude the use of alcoholic beverages and nicotine.
3. For 2-3 days it is not recommended to visit saunas and baths, take hot baths. You should also refrain from chemical peels.

At the beginning of the session, the beautician conducts a thorough examination of the patient's skin and asks the necessary questions. Taking an anamnesis will help you choose the correct method of drug administration. The doctor needs to find out if a person has allergic reactions and chronic diseases, how long ago the infections were transferred.

Refinex, reviews of cosmetologists about which they speak of a pronounced result, is used in the following sequence:

1. Cleansing... Remains of cosmetics, dirt and sebum are removed from the surface of the face and neck. The skin is treated with an antiseptic.
2. Inspection. A specialist examines the face and determines the injection sites and dosage. To do this, make active grimaces. In the process, it is possible to understand the characteristics of aging skin.
3. Consent. The patient draws up a document that indicates his consent to injections. Before that, it is recommended to check the quality certificate and expiration date of Refinex.
4. Anesthesia... Emla cream is used as anesthesia. The effect of the anesthetic begins after 20 minutes. after application.
5. Preparation... The cosmetologist must open the package with the drug strictly in the presence of the patient. The substance is diluted in the required dosage.
6. Introduction... At the marked points, the substance is injected into the dermis and hypodermis using the classical method. To do this, use a special thin needle and an insulin syringe. The allowed volume of substance in each muscle is 0.1 ml. It is inadmissible to get the needle into small vessels and capillaries. If this does happen, immediately pull out the needle and continue to inject the drug into another area.
7. Treatment... At the end of the procedure, an antiseptic agent and a soothing cream are applied to the skin. To prevent swelling, apply a cold compress.

For some time after the injections, do not strain the treated areas of the face. Otherwise, the drug is distributed unevenly in the tissues. Within 30 min. the patient remains under the supervision of a specialist. During this time, he makes recommendations for skin care in the coming days. The dosage of the substance is selected individually based on the location of the wrinkles, their depth and number.

The average volume of Refinex depending on the problem area is presented in the table:

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Contraindications

The procedure, despite its safe action, has a number of limitations. When planning an injection using Refinex, it is recommended to consult a specialist.

Active tuberculosis, renal failure, pathologies of the cardiovascular and respiratory systems are not strictly contraindications. Each case of manifestation of such deviations is considered individually.

Refinex, reviews of cosmetologists about which make it possible to avoid the serious consequences of the introduction, is strictly contraindicated in:

• myasthenia gravis;
• individual intolerance to the substances that make up the composition;
• Lambert-Eaton syndrome;
• pregnancy;
• high degree of myopia;
• critical days;
• under the age of 18;
• breastfeeding;
• damage to the skin;
• infectious and inflammatory diseases of the skin;
• chronic diseases in the acute stage;
• febrile conditions;
• autoimmune diseases;
• problems with blood clotting;
• disorders in the endocrine system;
• oncology;
• diabetes mellitus.

Side effects

You need to carefully select the dosage. Exceeding it contributes to the development of serious complications. The occurrence of side effects after Refinex is due to the high toxicity and other features of botulinum toxin. Counterfeiting can also be harmful to health.

Before use, Refinex requires a careful study of the list of side effects, as well as reviews of patients and cosmetologists. A doctor must admit a person to the procedure. Only a specialist can assess the possible risks of the drug.

Complications after the procedure include:

• asymmetry of the face with the wrong technology of drug administration;
• bruising and swelling at the puncture site;
• weakness of the muscles;
• dizziness;
• incomplete closure or drooping of the eyelids;
• violation of natural facial expressions;
• headache and migraine;
• renal and intestinal colic;
• tiredness and depression;
• temperature increase;
• ptosis of the skin;
• chills;
• diarrhea;
• vomiting;
• pain in the area of ​​the injection;
• dry mucous membranes and burning eyes.

Violation of the sterility of the conditions for the procedure leads to infection of the skin. Complications after the introduction of Refinex disappear on their own in 2-3 days, do not require intervention. In 10% of cases, unpleasant symptoms can appear as long as the substance is active. If unpleasant symptoms persist for more than 3 days, you should seek medical help.

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Opinions of doctors and cosmetologists

The reviews of cosmetologists about Refinexer are different. Many doctors are skeptical about the drug. Mistrust stems from a lack of information about the manufacturer. If the data is presented, then access to it is closed. Experts complain about fakes, which are common.

An experienced cosmetologist, Svetlana Sinitsyna, notes that the substance is of high quality. It is highly effective against the signs of aging. The action is similar to botox, because the composition includes the same component - botulinum toxin purified in stages.

The use of the substance rarely leads to allergies. In order not to lead to complications after the session, it is important to accurately calculate the dosage and correctly perform the injection.

The doctor is confused that the specified information about the manufacturers cannot be verified. No data could be found about the company mentioned. To protect yourself from a counterfeit substance, your doctor recommends buying the drug from a trusted supplier.

When to expect the effect

Already 2-3 hours after the session, the result becomes visible. It will intensify over several days. After a week, the effect obtained is assessed. If required, we can repeat the procedure. The effect lasts from 6 to 8 months.

There have been cases when patients did not notice any changes after the procedure. Experts explain that the lack of effect is due to the body's defensive reaction to the active ingredient. Active production of antibodies to botulinum toxin occurs in only 4% of people.

Refinex is a new generation drug in cosmetology, which is popular among modern women who care about beauty and health.

According to reviews, its use gives a high result in the fight against the signs of aging. The effect is pronounced and persists for a long time. The use of the product has a number of indications and serious side effects. Therefore, it is important to consult with your doctor before the procedure. Injections should be performed only by a highly qualified cosmetologist.

Article author: Pronina Marina

Article design: Ovsyanikova Svetlana

Video on the topic: the mechanism of action of the drug Refinex

Mechanism and speed of action of Refinex: