Mildronate for athletes. Action, instructions for the use of tablets, dosage

Mildronate is a familiar drug for athletes, they know firsthand how to take it. Initially, meldonium was used to solve problems of the cardiovascular system, but later it was actively used in people experiencing high physical activity.

Composition

The lion's share of the internal content of the drug is occupied by meldonium, this is an active substance developed by scientists as an analogue of gamma butyrobetaine (which is independently synthesized by the cells of the body). A synthetic substance of this kind has properties similar to the action of the B vitamin.

The drug is used as:

• angioprotector;
• cardioprotector;
• antihypoanalogsant.

Mildronath's action

The action of meldonium is based on the normalization of metabolic processes in the human body:

• inhibition of the production of carnitine, due to which the processes of fatty acid oxidation are inhibited;
• normalization of the work of physiological cellular processes;
• increased synthesis of gamma butyrobetaine, due to which there is a decrease in vasospasm and an increase in the rate of their purification from oxides;
• providing oxygen to all tissues and cells of the body;
• organization of glucose oxidation, due to which there is a decrease in the energy consumption of cells;
• reducing the likelihood of accumulation of free radicals by cells;
• increased contractility of the heart muscle.

Mildronate has such an effect on humans:

1. Increasing the overall endurance of the body.
2. Increased efficiency.
3. An increase in the level of tissue immunity.
4. Reducing the load on the heart muscle.

The effectiveness of the use of Mildronate

Mildronate effectively works not only for athletes, but also for ordinary people, both older and young, the main thing is to decide how to take it correctly. The effectiveness of the drug is confirmed by numerous clinical studies.

Regular and correct intake of meldonium allows you to achieve the following positive effects:

• accelerate muscle recovery after the transferred loads;
• increase the degree of elimination of toxins from the body;
• accelerate cellular and tissue regeneration;
• relieve symptoms of physical fatigue;
• to raise the muscle tone of the body;
• normalize blood circulation in organs and tissues;
• speed up metabolic processes;
• lower cholesterol;
• accelerate weight loss by increasing the rate of metabolism.

Contraindications

Meldonium does not have a large list of contraindications, which increases the availability of its use.

Taking the drug is prohibited only in some cases:

• for women who are pregnant, due to the lack of sufficient clinical studies of the effect of this drug on the female body and the fetus during this period;
• during lactation: scientists have not proven the possibility of meldonium penetration into breast milk, but to avoid potential harm to the baby, it is better not to take the drug;
• in the presence of individual intolerance one or more substances that make up the drug;
• patients with high intracranial pressure and tumor processes of various localization;
• for childrenunder the age of 12 (due to lack of proper research);
• while taking with nitroglycerin and adrenergic blockers, due to the possibility of a sharp decrease in pressure and an increase in heart rate;
• in patients with chronic liver disease and genitourinary system, with edema arising from an unknown reason.

The instructions for mildronate indicate how to take it for athletes, it also describes some restrictions:

• taking the drug in the morning to avoid the development of insomnia or the appearance of an overexcited state;
• meldonium is administered only intravenously or taken in capsule form, but not by intramuscular injection;
• for elderly people, the drug is prescribed for strict indications, in a slightly lower dosage than for other categories of patients (admission should be carried out under strict medical supervision).

Indications for use

Meldonium is used for a number of indications:

1. Diseases of the cardiovascular system: angina pectoris; myocardial infarction; ischemia; heart failure; strokes.
2. Decreased overall performance.
3. Retinal problems: retinopathy; hemophthalmos.
4. Increased physical and mental activity.

Application in sports

Mildronate has been actively used among athletes since the 70s of the 20th century, but in 2016 it was declared a prohibited drug among professional sports.

Athletes actively use this drug because of its such properties:

• improvement of cellular metabolism, due to which decay products are instantly removed from cells;
• accelerated energy recovery after tested physical exertion;
• increasing the overall endurance of the body.

Athletes prefer intravenous administration of the drug, due to the accelerated achievement of the expected effect compared to taking meldonium capsules.

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Slimming application

Considering the drug Mildronate for athletes how to take it, it is worth remembering that it is also indicated for those who want to lose weight.

The action of the drug, in this case, is as follows:

• metabolic processes in the body are greatly accelerated;
• increased efficiency when exercising in a gym or gym;
• the adaptive ability of the body to physical activity increases.

Losing weight through the use of Mildronate can be not so much accelerated as facilitated. This happens by increasing the overall endurance of the body (which is very important when working in the gym) and increasing the rate of calorie breakdown. Meldonium works like its analogue - carnitine.

Method of administration and dosage

Mildronate can be taken both in capsule form and by intravenous injection. Some people prefer intramuscular administration, but it does not provide the level of effectiveness achieved by the first two methods of administration.

The dosage and administration of the drug differs depending on the indications for which the drug is prescribed:

1. To fight cardiovascular diseases meldonium is taken orally at a dosage of 250 mg. Reception lasts for 4 days, followed by a break of 1 week. The scheme needs to be repeated.
2. When establishing normal cerebral circulation, Mildronate should be taken once a day at a dose of 500 mg. Such a scheme must be adhered to for 10 days, with the subsequent adjustment of the reception according to the recommendations of the attending physician.
3. During active and heavy physical exertion, as well as mental labor, Mildronate should be taken 3 to 4 times per knock, 250 mg each. The course lasts for 2 weeks, it must be repeated if necessary and according to indications.
4. Athletes who attend regular training sessions, is shown to take meldonium in a dose of 500 to 1000 mg 2 times a day. During the competition period, the drug may be taken continuously for 2 weeks.
5. To cleanse the body of alcohol intoxication, meldonium is taken 4 times a day, 500 mg. The therapeutic course is 1 week.

Injections of the drug are indicated for stroke, circulatory failure, cardiomyopathy, as more effective. The dosage depends on the specific case, in general, it varies from 5 to 10 ml of a single injection, twice a day.

Is there any harm from Mildronate?

Mildronate, like any other drug, is capable of bringing not only benefits to the human body, but also harm. This is especially true of the uncontrolled intake of the substance. It is very important to be attentive to the list of contraindications for taking meldonium.

The harm from the drug is primarily those people who are not recommended to take it.

Ideally, Mildronate should be taken under the supervision of a specialist who can stop its use in time in case of any non-standard reactions from the body.

Side properties of the drug

When deciding how to take mildronate, it is worth remembering the presence of side effects, the appearance of which is typical for both athletes and ordinary people.

The appearance of such effects is not an ordinary situation, their occurrence is rather an exception to the rule:

• a sharp change in blood pressure levels;
• the appearance of tachycardia;
• changes in the normal functioning of the digestive tract;
• the appearance of allergic reactions;
• the occurrence of headaches;
• overexcitation state.

With intravenous administration of the drug, the following reactions may occur:

• decrease in pressure;
• feeling of general weakness;
• increased heart rate;
• the appearance of dizziness.

It is possible to eliminate sudden side reactions of the body by stopping the intake of Mildronate and prescribing treatment for the symptoms that have arisen.

Timing of withdrawal from the body

The question of the timing of the removal of Mildronate outside the human body is very important for professional athletes. Since 2016, this drug has been recognized as doping, so taking it during competitions is outside the law.

This issue is not fully understood. Each source reports different information, the average time is about 24 hours, provided that Mildronate was used once. If we are talking about a systematic admission, then here the time for its complete elimination can vary from 3 to 5 months.

What do doctors say about Mildronate?

Meldonium is surrounded by a lot of rumors and all sorts of disputes regarding its effect on the body, possible benefits and harms. Nevertheless, the drug, over the entire history of its existence, not only contributed to the increase in endurance in athletes, but also saved many lives of patients with problems of the cardiovascular system.

According to L. Makarov professor, doctor of medical sciences, Mildronat has proven its positive influence over the years of application in sports medicine and cardiology.

The drug is actively used for its main focus - in order to improve the abilities of the cardiovascular system, increase its ability to withstand non-standard loads. Makarov notes that before the ban on WADA meldonium, it was actively taken by many athletes and invariably received good results.

Cardiologist V. Ivanov notes the high efficiency of the drug, both in the field of neurology and in cardiology.

However, in recent years, the clinical effect achieved by him has become somewhat lower, due to the deterioration in the quality of the drug.

Doping scandal

The ban on the use of meldonium in high-performance sports began in January 2016, after the scandal that occurred.Its essence lies in the detection of the components of this drug in doping tests of some athletes (among them there were 17% of Russian citizens) from different countries, including Germany, Ukraine, France and others.

Famous tennis player Maria Sharapova suffered from this scandal, whose team did not track the ban on the drug and was punished by WADA. In general, until the beginning of 2016, Mildronate was considered a vitamin preparation and was actively taken by almost all athletes in their professional activities.

To date, the athlete, in whose blood Mildronate will be found, will be suspended from competitive activity for a period of 4 years.

Although the studies conducted to date have not confirmed the effect of this substance on improving athletic performance.

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Analogues and prices

Mildronate is actively used for athletes, has several analogues, including the same active ingredient - Meldonium, which allows it to be taken as a vitamin or as a maintenance therapy.

All of them have the same effect on the human body, but differ only in the manufacturer and in the price policy:

• Idrinol: cost from 255 rubles;
• Cardionat price from 221 rubles;
• Riboxin price varies from 260 to 400 rubles;
• Melfor at a price of 240 rubles;
• Angiocardil worth from 197 rubles;
• Meldonium from 146 rubles;
• Medatern from 129 rubles;
• Midolat from 128 rubles;
• Energoton from 369 rubles;
• Cardazin from 120 rubles.

Mildronate is a drug that is actively prescribed to people with problems of the cardiovascular system. Nevertheless, it is often taken by athletes and people experiencing increased physical or mental stress, due to a positive effect on metabolic processes in the cells of the body.

How to take Mildronate for athletes: video

Milddronate in sports, advice from Dr. Draznin, see the video clip:

https://www.youtube.com/watch?v=GCGshJjX26M

Find out how Mildronate works in the video: