Glucosamin Chondroitin MSM is a medication that is prescribed to patients of different sex and age for the purpose of stopping degenerative-dystrophic processes in cartilage tissue. Reviews of the tool prove its effectiveness, but doctors recommend undergoing a diagnostic examination before starting the course.
Release form and composition of the drug
Available in small oval tablets with a neutral odor and taste... They are packaged in polyethylene bottles. Each such bottle can contain 90 tablets, which are also accompanied by instructions for use.
The bottle and instructions can be placed in a cardboard box. The pharmacological agent contains several active ingredients with various therapeutic properties. The main therapeutic effect is achieved due to the presence of glucosamine and chondroitin in tablets, as well as methylsulfonylmethane.
Additionally, the composition contains the following ingredients:
- Sodium.
- Potassium.
- Gelatin.
- Magnesium stearate.
- Silicon dioxide.
Additional components do not have therapeutic properties, but are necessary to give the correct shape and prevent changes in the composition under the influence of various factors.
Pharmacological properties
Glucosamin Chondroitin MSM, reviews of which are mostly positive, has several pharmacological properties. The most important is the ability to influence the processes of destruction of cartilage tissue in the articular joints and intervertebral discs.
The substances that make up the drug help, help stimulate the formation of chondrocytes and synovial fluid, which improves the mobility of the joints and prevents the progression of the pathological process.
In addition, the drug stimulates blood circulation, promotes the supply of nutrients to tissues, and also has anti-inflammatory properties. Due to the elimination of the expressed symptoms of the disease, the general condition of the patient improves, the pain is relieved, and the motor activity increases.
It is worth noting that the remedy has a regenerating effect, that is, it helps to speed up the healing process of tissues. This property makes it possible to use the agent not only in the therapy and prevention of degenerative-dystrophic changes.
Additionally, the medication stimulates the formation of collagen and hyaluronic acid in the body. These substances are extremely important for the joints and all tissues.
Pharmacodynamics and pharmacokinetics
The pharmacodynamics of the drug has been fully studied. After it enters the body, an active process of absorption of active components into the systemic circulation occurs. Chondroitin and glucosamine accumulate in the connective and cartilage tissue, as well as in the synovial fluid of the articular joints.
Due to the concentration in tissues in large quantities, the maximum therapeutic effect is achieved in a short period of time.2-3 weeks after the start of administration, there is a significant improvement, elimination of acute symptoms of inflammation and a slowdown in the pathological process.
Mobility in the spinal column or affected joints is restored, the pain becomes less pronounced.
Due to the active supply of blood and nutrients to the affected area, the process of tissue restoration, the formation of chondrocytes and synovial fluid begins. The remedy will not help to completely restore the affected cartilage at the advanced stage of the disease, but it can significantly improve the condition of the tissues.
The drug is actively involved in the metabolism of potassium in the body, therefore, helps to strengthen bones and improves the condition of the skin, muscles, ligaments. After completing the course of therapy, the patient notes not only an improvement in well-being, but also positive changes in the skin, hair and nails.
Pharmacokinetics of the drug begins after its penetration into the digestive tract. The active absorption process takes place in the patient's small intestine. Bioavailability of glucosamine reaches 23-26%, chondroitin - no more than 15%. The components bind rather poorly to blood proteins, but this does not weaken the effectiveness of the drug.
The processing of active substances occurs in the liver. The period of release of the body from glucosamine lasts up to 6 days. Chondroitin is completely eliminated within a day. The main amount of metabolites is excreted in the urine, a small part in the feces.
In patients with pathologies of the digestive tract and urinary system, the period of assimilation and excretion of the components is somewhat extended, which does not weaken the therapeutic effect.
Indications for use
Glucosamin Chondroitin MSM can be used in the treatment and prevention of many diseases.
Patient reviews confirm its effectiveness in the following cases:
- Arthrosis of 1 and 2 degrees, accompanied by pain and slight impairment of mobility.
- Professional sports involving severe stress on muscles, ligaments, joints and the spinal column.
- The recovery period after bone fractures, bruises and sprains of ligaments, muscles.
- Chronic osteochondrosis, but without pronounced changes in the fibrous ring of intervertebral discs.
- The presence of trophic ulcers and injuries on the limbs.
- Slow healing of wounds, cracks.
- Chronic vascular pathologies, for example, varicose veins, thrombophlebitis.
- Osteoporosis at the initial stage.
- Polyarthritis of rheumatoid origin, accompanied by severe inflammation, pain and local fever.
In addition, the product is sometimes used in cosmetology to improve the condition of hair, nails and skin, as well as to stimulate the process of tissue repair. However, the drug is most popular among professional athletes.
Contraindications
The tool has a pronounced effect on the body, therefore it has contraindications that should be considered before starting the intake. The biologically active additive is not used for the treatment of patients who have an intolerance to the components of the composition or a tendency to allergic manifestations.
You should not prescribe medication to children under 18 years old, as well as lactating and pregnant women. This can provoke complications. The medicine is contraindicated for severe renal and hepatic insufficiency, when its components cannot be normally processed in the body.
Another obstacle to starting treatment is considered an acute peptic ulcer or gastritis.... Only after the elimination of acute manifestations is it possible to take a course. For patients with severe heart disease, the drug is also prescribed with caution.
At what age can the drug be used
The medication is allowed to be taken only by patients over 18 years of age. This is due to the lack of data on the effect of the components on a fragile child's body.
Instructions for use, drug dosage
Glucosamin Chondroitin MSM (reviews of the tool should be studied before taking it) refers to dietary supplements, so it recommended to be taken with food, which will improve the absorption of active ingredients. It is also allowed to take tablets immediately after meals.
The daily dosage for an adult patient is 3 capsules, which must be taken at regular intervals or at a time. The minimum duration of a therapeutic course is at least 2 months. However, many experts prescribe a course of up to 3-4 months, which allows you to achieve the maximum therapeutic effect.
Repeat treatment, if necessary, is allowed after a 6 month break. It is important when using tablets to wash them down with plenty of clean water to facilitate dissolution.
The tablets should be swallowed whole, but if it is impossible to do this, it is allowed to pre-grind the product into powder and dissolve in 100 ml of water. This method is rarely used because the tablet is large enough to swallow whole.
Side effects
If the instructions for use are violated, the likelihood of developing negative reactions from the internal organs of the systems increases. However, complications can arise if all the rules are followed.
| Organs and systems | Most common symptoms |
| Nervous system | Dizziness, headache, insomnia, or persistent drowsiness. Sometimes there is impaired concentration and memory impairment. |
| Digestive system | Pain in the epigastric region is considered the most common negative manifestation. The patient may also develop flatulence, persistent constipation, sometimes nausea, poor appetite. Intestinal muscle spasms. |
| Heart and blood vessels | Tachycardia and a slight increase in blood pressure are the most pronounced manifestations when taking a dietary supplement. Usually such signs are observed in patients who suffer from chronic heart pathologies. |
| Skin | A rash on the skin may appear within a few hours after taking the first pill. In most cases, it is localized on the trunk, accompanied by itching and discomfort. |
Adverse reactions in each case are manifested individually. The patient may have only one deviation or several at once.
Overdose
Cases of overdose with the drug, with its correct use, have not been registered. But doctors draw the attention of patients to the need to follow the rules of treatment. When using too large a dosage of the drug at a time, there is an aggravation of adverse reactions from the internal organs.
The patient may have increased blood pressure, arrhythmia and pain in the heart. The headache worsens, accompanied by severe nausea, sometimes vomiting.
However, the most pronounced symptoms of overdose are observed on the part of the skin. The rash spreads over large areas, the itching becomes unbearable, and general allergy symptoms appear in the form of lacrimation and runny nose.
If symptoms of an overdose appear, you should immediately consult a doctor. Usually, the patient is gastric lavaged and therapy is prescribed to eliminate manifestations.
special instructions
Glucosamin Chondroitin MSM, reviews of which are considered additional confirmation of the quality of the product, not effective for patients suffering from advanced forms of osteochondrosis or arthrosis.
This is due to the almost complete absence of a cartilaginous layer in this course of pathology, which does not allow the active components to accumulate in the tissue. However, as an auxiliary method of treatment, medication is used quite often.
If mild negative reactions are observed in the first few days of therapy, it is worth reducing the dosage by 2 times. If there is no improvement, treatment should be stopped.
It is important to normalize the diet, include liver, chicken and beef meat. You should definitely eat seafood, as well as gelatin-based dishes.Compliance with the recommendations will improve the effectiveness of therapy.
Drug interactions
- External remedies based on glucosamine and chondroitin can be combined with a dietary supplement. This will not affect the result and will not provoke an overdose.
- It is not recommended to take the drug at the same time as antibiotics of the tetracycline series, as this increases the rate of absorption of the latter. The effect of penicillin and antibiotics based on it is weakened when taken simultaneously with medications.
- It is allowed to combine the drug with non-steroidal anti-inflammatory drugs. And also glucocorticoids.
Analogs
There are many drug substitutes with similar chemical composition and properties.
The most commonly prescribed are the following:
- Glucosamine-Chondroitin Complex from Doppelherz is available in tablet form. It is recommended to take it for 3-4 months. Repeat the course 2 times a year. The tool is effective and safe.
- Teraflex - a medication in which the amount of chondroitin is slightly higher than the dosage of glucosamine. It has anti-inflammatory, analgesic and regenerative effects, improves the condition of cartilage and connective tissue.
- Artra - another chondroprotector based on glucosamine and chondroitin. It helps to improve the condition in arthrosis and osteochondrosis, it is prescribed to patients during the recovery period after injuries.
Any of the analogues is highly effective, but you can take it after consulting a doctor.
Terms, conditions of sale and storage
The dietary supplement is available over the counter without a prescription. It is allowed to store tablets for 24 months, the manufacturer indicates the date of manufacture on the package. The maximum storage temperature should not exceed +250C. It is important to protect the product from children.
Price in pharmacies in Moscow, St. Petersburg, regions
The cost of a medicine in regional pharmacies, for example, Taganrog, Voronezh or Belgorod, starts from 600 rubles. for 90 tablets. In St. Petersburg and Moscow, you can buy it for 800-900 rubles.
Glucosamin Chondroitin MSM is a popular chondroprotective agent that has a pronounced effect on cartilage, connective and bone tissue.
Feedback from patients confirms the effectiveness of the drug, which allows it to be actively used for therapy and prevention of many pathologies.
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Description of the drug Glucosamin Chondroitin MSM: